Glioblastoma is carcinogenesis of glial cells in central nervous system and has the highest incidence among primary brai......

The p110α,catalytic subunit of PI3Kα,was the primary phosphoinositide 3-kinases (PI3Ks)isoform involved in oncogenic R......

Aim Chronic myelogenous leukemia (CML) is a hematopoietic stem cell cancer caused by the BcrAbl tyrosine kinase which ar......

HL-60 cell line was originated from a female patient with acute promyelocytic leukemia(APL),whose features have made its......

Phosphoinositide 3-kinase(PI3K)is an attractive target to potentially treat a range of disease stales as illustrated by ......

目的以PI3K/Akt/mTOR信号转导通路为靶点，观察PI3K抑制剂LY294002和mTOR抑制剂RAD001对体外培养血管瘤内皮细胞增殖与凋亡的影响，并......